1758

Franciscan missionaries established Mission Santa Cruz de San Sabá in 1757 to Christianize the eastern Apache Indians.

Santa Clara Pueblo was first visited in 1541 by part of Francisco Vásquez de Coronado's expeditionary force. A mission was established in 1628 as a visita  for San Juan Pueblo. In 1680 the inhabitants of Santa Clara took an active part in the Great Pueblo Revolt against the Spanish.