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Oldest mission site yet discovered in Spanish Texas, the oldest European site yet discovered in East Texas and the oldest site yet discovered known to bear the name Tejas.

Nuestra Señora de la Concepción del Socorro was founded in 1682 by the Franciscan order to serve displaced American Indians (the Piro, Tano and Jemez) from New Mexico, who fled during the Pueblo Revolt.

Ysleta Mission was constructed in 1744 in part to serve the Tigua Indian community which had fled New Mexico during the Pueblo Revolt. The site was also known by the Spaniards as Corpus Christi de la Isleta.

Santa Clara Pueblo was first visited in 1541 by part of Francisco Vásquez de Coronado's expeditionary force. A mission was established in 1628 as a visita  for San Juan Pueblo. In 1680 the inhabitants of Santa Clara took an active part in the Great Pueblo Revolt against the Spanish.

The mission was built as one of the four missions among the Piro Pueblos between 1615 and 1626 through the Camino Real. This mission was partly destroyed after the Pueblo Revolt and only portions of the old church remains, including parts of the adobe walls and beams.

Positioned in the mountains north of Santa Fe on the high road to Taos, the pueblo of Pícuris remains small and quiet. Fray Francisco de Zamora was charged with the establishment of the permanent mission, which was built around 1620.

San Juan Pueblo is known as the first Spanish settlement in the Southwest. After the recolonization of New Mexico by the Spanish in 1692, a mission complex was built to serve the Ohkay Owingeh Pueblo.

Construction of this mission began in 1627 by Fray Juan Gutiérrez de la Chica. At its peak, the Quarai pueblo had approximately 1,000 rooms and housed between 600 and 700 residents of both native and Spanish decent. The pueblo buildings were arranged around a number of small plazas.

The first church at the Pecos Pueblo was probably built by the Franciscan Fray Pedro Zambrano Ortiz by 1619. The people of the pueblo would not allow construction of a church closer to their dwellings.

San Xavier del Bac is located Southwest of Tucson, Arizona. Founded in 1692 by Father Eusebio Francisco Kino. The current mission construction started in 1781by Father Juan Bautista Velderrain and terminated in 1797 under Father Juan Bautista Llorens.

Started by Father Antonio de San Buenaventura y Olivares in 1716, this National and State Historic Landmark was originally located west of San Pedro Springs. It survived three moves. During the 19th century struggle for political and military control of Texas.